Laryngeal tuberculosis: about 04 cases

Pan Afr Med J. 2023 Aug 31:45:193. doi: 10.11604/pamj.2023.45.193.5325. eCollection 2023.

Abstract

The purpose of this study is to present epidemiological, clinical, radiological, histological characteristics and treatment of laryngeal tuberculosis. It is also aimed at making the point about diagnosis difficulties. This retrospective study was conducted over three years; it concerned 4 cases, 3 males and one female. The average age was 35 years. Three of the 4 cases have had a cervical CT scan. All patients have had a laryngoscopy with biopsy and anatomopathological study. The onset modes of the disease have been progressive for all the patients. Topographical study has shown two epiglottic locations, one at the vocal cords and the other one at the posterior commissure. The diagnosis was orientated in the 3 cases by the CT scan and confirmed by anatomopathological exam in all cases. All patients have received anti-TB drugs with good evolution. The laryngeal location of tuberculosis is unusual. The clinical picture is nonspecific, raising the issue of differential diagnosis with tumor pathology. Sectional imaging and CT scan can guide the diagnosis and a positive diagnosis is often discovered on the occasion of a tumor biopsy of a pseudo-tumor lesion. Treatment is based on anti-TB drugs.

Keywords: Tuberculosis; anti-TB drugs; ear; extra nodal; larynx; nose and throat.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Laryngoscopy
  • Larynx* / pathology
  • Male
  • Neoplasms* / pathology
  • Retrospective Studies
  • Tuberculosis, Laryngeal* / diagnosis
  • Tuberculosis, Laryngeal* / drug therapy
  • Vocal Cords / pathology