Objective: To explore the effect of early rehabilitation training on motor function and neural function of patients with brainstem hemorrhage after stereotactic individualized operation. Methods: A total of 84 patients with brainstem hemorrhage after stereotactic individualized surgery admitted to Nanyang Central Hospital from January 2020 to January 2022 were selected as the study subjects.The patients were randomly divided into observation group (n=42) and control group (n=42) according to random number table method. The control group received conventional Western medicine treatment, and the observation group received early rehabilitation training on the basis of drug treatment in the control group. The motor function assessment [Fugl Meyer Assessment (FMA) scores], neural function [National Institutes of Health Stroke Scale (NIHSS) scores], ability of daily living [Barthel index (BI) scores], cerebral blood flow [mean blood flow (MBF), mean flow velocity (MFV), peripheral vascular resistance (PVR)] and nerve factor [serum neuron specific enolase (NSE), brain derived neurotrophic factor (BDNF), central nervous specific protein(S100β)] levels were compared between the two groups before and after the treatment. In addition, the rehabilitation effect and complications of the two groups were observed. Results: The total effective rate (95.24%) in the observation group was higher than that in the control group (76.19%%) (P<0.05). After the treatment, the FMA scores, BI scores, MBF, MFV and BDNF levels of the two groups were higher than those before the treatment, and the observation group were higher than the control group (P<0.05). NIHSS scores, PVR, NSE and S100β levels in the two groups after the treatment were lower than those before the treatment, and those in the observation group were lower than those in the control group (P<0.05). The incidence of complications in the observation group [7.14% (3/42)]was lower than that in the control group [23.81% (10/42), P<0.05]. Conclusion: For patients with brain stem hemorrhage after stereotactic individualized surgery, early rehabilitation training can improve the motor, neural function and daily living ability, rehabilitation effect, regulate cerebral hemodynamics and nerve factor levels, and reduce the incidence of complications.
目的： 探讨早期康复训练对脑干出血患者立体定向个体化术后运动功能和神经功能的影响。 方法： 前瞻性选择2020年1月至2022年1月南阳市中心医院收治的84例立体定向个体化术后脑干出血患者为研究对象，按随机数字表法分为观察组（n=42）与对照组（n=42），对照组予常规西医治疗，观察组在对照组药物治疗基础上行早期康复训练治疗，比较两组治疗前后运动功能评定［Fugl-Meyer（FMA）评分］、神经功能［美国国立卫生研究院卒中量表（NIHSS）评分］及日常生活能力［Barthel指数（BI）评分］、脑血流情况［平均血流量（MBF）、平均流速（MFV）、周围血管阻力（PVR）］及神经因子［血清神经元特异性烯醇化酶（NSE）、脑源性神经营养因子（BDNF）、中枢神经特异性蛋白（S100β）］水平，观察两组康复效果和并发症情况。 结果： 观察组总有效率［95.24%（40/42）］高于对照组［76.19%（32/42）］（P<0.05）；治疗后两组FMA评分、BI评分、MBF、MFV及BDNF水平均较治疗前高（均P<0.05），观察组均较对照组高（均P<0.05）；治疗后两组NIHSS评分、PVR、NSE及S100β水平较治疗前低（均P<0.05），观察组均较对照组低（均P<0.05）；观察组并发症发生率［7.14%（3/42）］低于对照组［23.81%（10/42），P<0.05］。 结论： 在脑干出血患者立体定向个体化术后行早期康复训练，可改善运动、神经功能及日常生活能力，提高康复效果，调节脑血流动力学和神经因子水平，降低并发症发生率。.