Eco-friendly monitoring of triclosan as an emerging antimicrobial environmental contaminant utilizing electrochemical sensors modified with CNTs nanocomposite transducer layer

BMC Chem. 2023 Nov 28;17(1):170. doi: 10.1186/s13065-023-01092-0.

Abstract

Environmental appearance of antimicrobials due to frequent use of personal care products as recommended by WHO can cause serious flare-up of antimicrobial resistance. In this work, three eco-friendly microfabricated copper solid-state sensors were developed for measuring triclosan in water. Multi-walled carbon nanotubes were incorporated in sensor 2 and 3 as hydrophobic conductive inner layer. Meanwhile, β-cyclodextrin was incorporated in sensor 3 as an ionophore for selective binding of TCS in presence of interfering compounds. The obtained linear responses of sensors 1, 2 and 3 were (1 × 10- 8-1 × 10- 3 M), (1 × 10- 9-1 × 10- 3 M) and (1 × 10- 10- 1 × 10- 3 M), respectively. Limit of detection was 9.87 × 10- 9 M, 9.62 × 10- 10 M, and 9.94 × 10- 11 M, respectively. The miniaturized sensors were utilized for monitoring of triclosan in water samples.

Keywords: Antimicrobial resistance; Coronavirus disease-19; Emerging contaminants; Green analysis; Solid contact ISEs; Triclosan.