Therapeutic use of medical Cannabis in neurological diseases: a clinical update

J Neural Transm (Vienna). 2024 Feb;131(2):117-126. doi: 10.1007/s00702-023-02719-1. Epub 2023 Nov 28.

Abstract

The use of medical Cannabis has increased in recent years due to changing legal circumstances in many countries. Approval exists only for a few neurological conditions such as rare forms of epilepsy or spasticity in multiple sclerosis. Beyond that, however, medical Cannabis is used for a wide range of neurological conditions and symptoms. In Germany, in parallel with new legislation that has simplified the prescription of medical Cannabis, an accompanying survey has been implemented for which initial data are now available. In this context, our review provides an overview of the evidence for the therapeutic use of medical Cannabis in neurology, the potential benefits, and side effects.

Keywords: Cannabinoids; Cannabis; Neurological diseases; Neurology; THC.

Publication types

  • Review

MeSH terms

  • Epilepsy* / drug therapy
  • Germany
  • Humans
  • Medical Marijuana* / therapeutic use
  • Multiple Sclerosis* / complications
  • Multiple Sclerosis* / drug therapy
  • Muscle Spasticity / drug therapy
  • Muscle Spasticity / etiology

Substances

  • Medical Marijuana