Prostate tuberculosis mimicking prostate cancer: Case report and literature review

Medicine (Baltimore). 2023 Nov 24;102(47):e36172. doi: 10.1097/MD.0000000000036172.

Abstract

Rationale: Prostate tuberculosis (PTB) has no specific symptoms, or insidious presentation in male reproductive system tuberculosis, and is difficult to detect in the early stage. When PTB develops to the late stage, it leads to disease progression and irreversible organ and tissue damage. At present, the imaging manifestations of prostate tuberculosis vary and are not well known to imaging physicians and urologists.

Diagnoses and interventions: This case was a PTB patient, whose main manifestation was elevated serum prostate-specific antigen and the diagnosis was confirmed by ultrasound-guided prostate biopsy. We analyzed the imaging performance of various imaging techniques, and summarized and explored the imaging characteristics reported in the previous literature, with the aim of improving the early detection rate and providing evidence-based practice for early regular antituberculosis treatment in PTB.

Outcomes: The multiparametric transrectal ultrasound performance of PTB is characteristic, and can be used for the differential diagnosis of prostate cancer causing elevated prostate-specific antigen levels in aged men.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Image-Guided Biopsy / methods
  • Magnetic Resonance Imaging / methods
  • Male
  • Prostate / diagnostic imaging
  • Prostate / pathology
  • Prostate-Specific Antigen
  • Prostatic Neoplasms* / pathology
  • Prostatitis*
  • Tuberculosis, Male Genital* / diagnosis
  • Tuberculosis, Male Genital* / drug therapy

Substances

  • Prostate-Specific Antigen