Allergen Immunotherapy for Asthma

J Allergy Clin Immunol Pract. 2024 Jan;12(1):23-30. doi: 10.1016/j.jaip.2023.11.031. Epub 2023 Nov 25.

Abstract

Allergen immunotherapy is a disease-modifying treatment for IgE-mediated allergies reducing disease burden and symptoms in patients with allergic rhinitis, with or without asthma. The growing evidence that allergen immunotherapy also has the potential to facilitate achieving asthma control in patients with allergic asthma resulted in its acknowledgment by international bodies (Global Initiative for Asthma and European Academy of Allergy and Clinical Immunology) as add-on treatment for mild/moderate asthma. Although there have been promising developments in biomarkers for patient selection and for allergen immunotherapy efficacy evaluation in patients with asthma, a lot more data are still required.

Keywords: Allergy; Clinical; Immunotherapy; SCIT; SLIT; Treatment.

MeSH terms

  • Allergens
  • Asthma* / diagnosis
  • Biomarkers
  • Desensitization, Immunologic / methods
  • Humans
  • Hypersensitivity, Immediate*
  • Rhinitis, Allergic* / diagnosis
  • Sublingual Immunotherapy*

Substances

  • Biomarkers
  • Allergens