Methylphenidate-associated chest pain in a child

BMJ Case Rep. 2023 Nov 27;16(11):e255187. doi: 10.1136/bcr-2023-255187.

Abstract

A young child was diagnosed with autism spectrum disorder with comorbid attention-deficit/hyperactivity disorder. His hyperactivity, impulsivity and absence of awareness towards danger increased his risk of harm and hence methylphenidate was indicated. Unfortunately, he developed chest pain eight months after the treatment initiation. We then stopped the stimulant and changed his treatment to atomoxetine, after which he no longer had chest pain. In the following illustrated case, we will discuss the cardiac side effect of methylphenidate.

Keywords: Child and adolescent psychiatry; Child and adolescent psychiatry (paediatrics); Developmental paediatrics; Psychiatry (drugs and medicines); Unwanted effects / adverse reactions.

Publication types

  • Case Reports

MeSH terms

  • Attention Deficit Disorder with Hyperactivity* / drug therapy
  • Autism Spectrum Disorder* / drug therapy
  • Central Nervous System Stimulants* / adverse effects
  • Chest Pain / chemically induced
  • Chest Pain / drug therapy
  • Child
  • Humans
  • Male
  • Methylphenidate* / adverse effects

Substances

  • Methylphenidate
  • Central Nervous System Stimulants