In this prospective study, patients on home parenteral nutrition were twice as likely to be colonized with Staphylococcus aureus if their caregivers were carriers. Among S. aureus-positive patients and their caregivers, molecular analysis showed 68% genetically related strains. Despite decolonization, genetically related strains reappeared in 70% of patients.
Keywords: Staphylococcus aureus carriage; decolonization treatment; home parenteral nutrition; transmission; whole-genome sequencing.
© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.