How effective were Australian Quarantine Stations in mitigating transmission aboard ships during the influenza pandemic of 1918-19?

PLoS Comput Biol. 2023 Nov 27;19(11):e1011656. doi: 10.1371/journal.pcbi.1011656. eCollection 2023 Nov.

Abstract

The influenza pandemic of 1918-19 was the most devastating pandemic of the 20th century. It killed an estimated 50-100 million people worldwide. In late 1918, when the severity of the disease was apparent, the Australian Quarantine Service was established. Vessels returning from overseas and inter-state were intercepted, and people were examined for signs of illness and quarantined. Some of these vessels carried the infection throughout their voyage and cases were prevalent by the time the ship arrived at a Quarantine Station. We study four outbreaks that took place on board the Medic, Boonah, Devon, and Manuka in late 1918. These ships had returned from overseas and some of them were carrying troops that served in the First World War. By analysing these outbreaks under a stochastic Bayesian hierarchical modeling framework, we estimate the transmission rates among crew and passengers aboard these ships. Furthermore, we ask whether the removal of infectious, convalescent, and healthy individuals after arriving at a Quarantine Station in Australia was an effective public health response.

MeSH terms

  • Australia / epidemiology
  • Bayes Theorem
  • Disease Outbreaks / prevention & control
  • Hospitals, Isolation
  • Humans
  • Influenza, Human* / epidemiology
  • Influenza, Human* / prevention & control
  • Pandemics / prevention & control
  • Ships*
  • Travel

Grants and funding

P.A. was supported by a Melbourne Research Scholarship from the University of Melbourne. P.G.T. would like to acknowledge the support of the Australian Research Council via the Centre of Excellence for Mathematical and Statistical Frontiers (ACEMS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.