Pushing the Detection Limit of Static Wideline NMR Spectroscopy Using Ultrafast Frequency-Swept Pulses

Jonas Koppe; Joop Enno Frerichs; Michael Ryan Hansen

doi:10.1021/acs.jpclett.3c02758

Pushing the Detection Limit of Static Wideline NMR Spectroscopy Using Ultrafast Frequency-Swept Pulses

J Phys Chem Lett. 2023 Dec 7;14(48):10748-10753. doi: 10.1021/acs.jpclett.3c02758. Epub 2023 Nov 27.

Authors

Jonas Koppe^{1

2}, Joop Enno Frerichs¹, Michael Ryan Hansen^{1

3}

Affiliations

¹ Institute for Physical Chemistry, University of Münster, Corrensstrasse 28/30, DE-48149 Münster, Germany.
² Centre de RMN Très Hauts Champs de Lyon (UMR5082 - CNRS, ENS Lyon, UCB Lyon 1), Université de Lyon, 5 rue de la Doua, 69100 Villeurbanne, France.
³ Center for Multiscale Theory and Computation (CMTC), University of Münster, Corrensstrasse 40, DE-48149 Münster, Germany.

PMID: 38010530
DOI: 10.1021/acs.jpclett.3c02758

Abstract

We report a simple design strategy for wideband uniform-rate smooth truncation (WURST) pulses that enables ultrafast frequency sweeps to maximize the sensitivity of Carr-Purcell-Meiboom-Gill (CPMG) acquisition in static wideline nuclear magnetic resonance (NMR). Three compelling examples showcase the advantage of ultrafast frequency sweeps over currently employed WURST-CPMG protocols, demonstrating the potential of investigating materials that are typically inaccessible to static wideline NMR techniques, e.g., paramagnetic solids with short homogeneous transverse relaxation times.