Critical elements of pediatric testicular germ cell tumors surgery

Amanda F Saltzman; Patrick Hensley; Jonathan Ross; Lynn Woo; Deborah Billmire; Frederick Rescorla; Dhruv Puri; Sunil Patel; Phillip Pierorazio; Aditya Bagrodia; Clint Cary; Nicholas G Cost

doi:10.1016/j.sempedsurg.2023.151343

Critical elements of pediatric testicular germ cell tumors surgery

Semin Pediatr Surg. 2023 Oct;32(5):151343. doi: 10.1016/j.sempedsurg.2023.151343. Epub 2023 Nov 17.

Authors

Affiliations

¹ Department of Urology, University of Kentucky, Lexington, KY, USA.
² Department of Urology, Rush University, Chicago, IL, USA.
³ Department of Urology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
⁴ Department of Pediatric Surgery, Indiana University School of Medicine and Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
⁵ Department of Urology, University of California San Diego, La Jolla, CA, USA.
⁶ Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁷ Department of Urology, Penn Medicine, Philadelphia, PA, USA.
⁸ Department of Urology, Indiana University, Indianapolis, IN, USA.
⁹ Division of Urology, Department of Surgery at the University of Colorado School of Medicine, Aurora, CO, USA; The Surgical Oncology Program, Children's Hospital Colorado, Aurora, CO, USA. Electronic address: Nicholas.Cost@childrenscolorado.org.

PMID: 38006835
DOI: 10.1016/j.sempedsurg.2023.151343

Abstract

Children, adolescents and young adults with testicular germ cell tumors require appropriate surgical care to insure excellent outcomes. This article presents the most critical elements, and their basis in evidence, for surgery in this population. Specifically, the importance of inguinal radical orchiectomy for malignant tumors, partial orchiectomy for prepubertal tumors and normal serum tumor markers, and the appropriate use of post-chemotherapy retroperitoneal lymph node dissection in those with residual retroperitoneal masses.

Keywords: Adolescent; Pediatric; Testicular cancer; Urologic oncology; Young adult.

MeSH terms

Adolescent
Child
Humans
Lymph Node Excision
Male
Neoplasms, Germ Cell and Embryonal* / surgery
Orchiectomy
Testicular Neoplasms* / drug therapy
Testicular Neoplasms* / pathology
Testicular Neoplasms* / surgery
Young Adult

Supplementary concepts

Testicular Germ Cell Tumor