Rosellosides A and B, two phenyloxazole glycosides from Glycyrrhiza inflata-derived fungus Rosellinia sp. Glinf021

Gan Gu; Xuwen Hou; Jiayin Zhang; Xiaoqian Pan; Dan Xu; Daowan Lai; Ligang Zhou

doi:10.1080/14786419.2023.2285867

Rosellosides A and B, two phenyloxazole glycosides from Glycyrrhiza inflata-derived fungus Rosellinia sp. Glinf021

Nat Prod Res. 2023 Nov 24:1-5. doi: 10.1080/14786419.2023.2285867. Online ahead of print.

Authors

Gan Gu¹, Xuwen Hou¹, Jiayin Zhang¹, Xiaoqian Pan¹, Dan Xu¹, Daowan Lai¹, Ligang Zhou¹

Affiliation

¹ Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.

PMID: 37999995
DOI: 10.1080/14786419.2023.2285867

Abstract

Two new chlorinated phenyloxazole glycosides, named rosellosides A (1) and B (2), were isolated from the endophytic fungus Rosellinia sp. Glinf021, which was derived from the medicinal plant Glycyrrhiza inflata (Leguminosae). Both compounds were rare chlorinated polyketide glycosides bearing an oxazole moiety. Their structures were elucidated by analysis of the NMR and HRESIMS data, and their absolute configurations were determined by quantum chemical ECD calculations and X-ray crystallography.

Keywords: Endophytic fungus; Glycyrrhiza inflata; Rosellinia sp. Glinf021; chlorinated phenyloxazole glycosides; rosellosides A and B.