Adhesion GPCRs in glioblastoma revisited

Tobias Langenhan

doi:10.1016/j.celrep.2023.113474

Adhesion GPCRs in glioblastoma revisited

Cell Rep. 2023 Dec 26;42(12):113474. doi: 10.1016/j.celrep.2023.113474. Epub 2023 Nov 22.

Author

Tobias Langenhan¹

Affiliation

¹ Rudolf Schönheimer Institute of Biochemistry, Division of General Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany; Comprehensive Cancer Center Central Germany (CCCG), Germany; Institute of Biology, Faculty of Life Sciences, Leipzig University, Leipzig, Germany. Electronic address: tobias.langenhan@gmail.com.

PMID: 37995190
DOI: 10.1016/j.celrep.2023.113474

Abstract

Glioblastoma is a devastating brain malignancy that has remained intractable to modern cancer treatments. Ravn-Boess et al.¹ have discovered that the adhesion G protein-coupled receptor CD97/ADGRE5 contributes to glioblastogenesis and makes for an excellent molecular surface marker flagging the tumor cells.

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MeSH terms

Glioblastoma* / pathology
Humans
Receptors, G-Protein-Coupled

Substances

Receptors, G-Protein-Coupled