Predictive value of the five-repetition sit-to-stand test for outcomes after surgery for lumbar disc herniation: prospective study

Eur Spine J. 2024 Mar;33(3):956-963. doi: 10.1007/s00586-023-08046-z. Epub 2023 Nov 22.

Abstract

Objective: It is unknown whether presence of pre-operative objective functional impairment (OFI) can predict post-operative outcomes in patients with lumbar disc herniation (LDH). We aimed to determine whether pre-operative OFI measured by the five-repetition sit-to-stand test (5R-STS) could predict outcomes at 12-months post-discectomy.

Methods: Adult patients with LDH scheduled for surgery were prospectively recruited from a Dutch short-stay spinal clinic. The 5R-STS time and patient reported outcome measures (PROMs) including Oswestry Disability Index, Roland-Morris Disability Questionnaire, Visual Analogue Scale (VAS) for back and leg pain, EQ-5D-3L health-related quality of life, EQ5D-VAS and ability to work were recorded pre-operatively and at 12-months. A 5R-STS time cut-off of ≥ 10.5 s was used to determine OFI. Mann-Whitney and Chi-square tests were employed to determine significant differences in post-operative outcomes between groups stratified by presence of pre-operative OFI.

Results: We recruited 134 patients in a prospective study. Twelve-month follow-up was completed by 103 (76.8%) patients. Mean age was 53.2 ± 14.35 years and 50 (48.5%) patients were female. Pre-operatively, 53 (51.5%) patients had OFI and 50 (48.5%) did not. Post-operatively, patients with OFI experienced a significantly greater mean change (p < 0.001) across all PROMs compared to patients without OFI, except leg pain (p = 0.176). There were no significant differences in absolute PROMs between groups at 12-months (all p > 0.05).

Conclusions: The presence of OFI based on 5R-STS time does not appear to decrease a patient's likelihood of experiencing satisfactory post-operative outcomes. The 5R-STS cannot predict how a patient with LDH will respond to surgery at 12-month follow-up.

Keywords: Functional impairment; Lumbar disc herniation; Objective test; Sit to stand.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Intervertebral Disc Degeneration* / surgery
  • Intervertebral Disc Displacement* / surgery
  • Lumbar Vertebrae / surgery
  • Male
  • Middle Aged
  • Pain / surgery
  • Prospective Studies
  • Quality of Life
  • Treatment Outcome