Hepatomegaly is an autosomal recessive condition with an estimated 1:30000 cases worldwide. Because the symptoms and indicators of hepatomegaly mental disease are poorly understood, the ailment is frequently misdiagnosed or underdiagnosed, which causes irreparable nerve damage in the patient's later years. To comprehensively review the research and offer a list of treatments for treating mental illnesses in hepatomegaly. PRISMA guidelines were used to deliver the review. Evidence-based nursing standards were used to design research questions and tactics. In order to find information on hepatomegaly clinical guidelines, systematic reviews, randomized controlled trials (RCTs), and expert consensus on the management of mental disorders in patients with nuclear degeneration, all databases of CINAHL, Up to Date, the Cochrane Library, Pubmed(Medline), Embase, Wiley, JBI, International Guidelines.com, Wanfang, and CNKI were searched. This investigation covered a total of 14 publications, and 41 best evidence items, encompassing screening, evaluation, clinical symptoms, pharmaceutical therapies, non-pharmacological interventions, and health education, were retrieved. It is recommended that healthcare professionals evaluate our cultural characteristics, medical resources, and patient's subjective and objective conditions before clinical application, apply the evidence in a targeted manner to improve patient's health outcomes, and reduce readmissions. The 41 best evidence for patients with hepatomegaly can guide the treatment and rehabilitation of patients with hepatomegaly and psychiatric disorders.
Keywords: Evidence to summarize; Hepatomegaly; Management; Mental Disorders; Screening.