Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach

Curr Allergy Asthma Rep. 2023 Nov;23(11):621-634. doi: 10.1007/s11882-023-01111-z. Epub 2023 Nov 22.

Abstract

Purpose of review: A modified Delphi process was undertaken to provide a US expert-led consensus to guide clinical action on short-acting beta2-agonist (SABA) use. This comprised an online survey (Phase 1), forum discussion and statement development (Phase 2), and statement adjudication (Phase 3).

Recent findings: In Phase 1 (n = 100 clinicians), 12% routinely provided patients with ≥4 SABA prescriptions/year, 73% solicited SABA use frequency at every patient visit, and 21% did not consult asthma guidelines/expert reports. Phase 3 experts (n = 8) reached consensus (median Likert score, interquartile range) that use of ≥3 SABA canisters/year is associated with increased risk of exacerbation and asthma-related death (5, 4.75-5); SABA use history should be solicited at every patient visit (5, 4.75-5); usage patterns over time, not absolute thresholds, should guide response to SABA overuse (5, 4.5-5). Future asthma guidelines should include clear recommendations regarding SABA usage, using expert-led thresholds for action.

Keywords: Asthma; Asthma guidelines; Delphi consensus; Exacerbations; Reliever inhaler; SABA overuse.

Publication types

  • Review

MeSH terms

  • Administration, Inhalation
  • Anti-Asthmatic Agents* / administration & dosage
  • Anti-Asthmatic Agents* / adverse effects
  • Asthma* / drug therapy
  • Clinical Decision-Making
  • Consensus
  • Delphi Technique
  • Humans
  • Surveys and Questionnaires

Substances

  • Anti-Asthmatic Agents