Acetylenyl substituted nucleic bases and their triphenylphosphonium (TPP) conjugates. Unexpected surge in cytotoxicity

Bioorg Chem. 2024 Jan:142:106959. doi: 10.1016/j.bioorg.2023.106959. Epub 2023 Nov 7.

Affiliations

¹ Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str. 8, Kazan 420088, Russian Federation.
² Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str. 8, Kazan 420088, Russian Federation. Electronic address: sobaka-1968@mail.ru.

PMID: 37988977
DOI: 10.1016/j.bioorg.2023.106959

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drug Carriers*
Drug Delivery Systems*
Organophosphorus Compounds / pharmacology

Substances

triphenylphosphonium
Drug Carriers
Organophosphorus Compounds