Surfactants derived from renewable resources and synthesized using renewable feedstock and sustainable methods have become a major research focus over the past decade in the surfactant industry. This research presents an approach for rapidly converting readily available polysaccharides, like pectin derived from fruit waste, into safely biodegradable surface-active polymers. Commercially available pectin was modified with n-alkyl amines having different alkyl chain lengths using potassium carbonate as a catalyst. The effect of pectin molecular weight, alkyl chain length and degree of substitution (DS) on surface-active properties of the modified pectin derivatives was studied. Surface tension decreased slightly with lowering molecular weight, whereas interfacial tension decreased dramatically. Cytotoxicity evaluations using human dermal fibroblast, HepG2 and Jurkat cells demonstrated that these polysaccharide-based surfactants exhibit lower cytotoxicity compared to the conventional surfactants such as octyl phenol ethoxylates (i.e., Triton™ X-100), and therefore are more environmentally friendly. Biodegradation studies show that all modified pectins are "ultimately biodegradable" except for Pectin-amide C8 (1:10).
Keywords: Amide modification; Biodegradation; Cytotoxicity; Pectin-based surfactant; Structure-property relationship.
Copyright © 2023. Published by Elsevier Ltd.