Ultrasound Characteristics of Metastatic Occult Cervical Lymph Nodes in Early Tongue Cancer

Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):2786-2791. doi: 10.1007/s12070-023-03881-4. Epub 2023 May 15.

Abstract

Introduction: Identification of occult lymph node metastasis is challenging in early tongue cancers. We conducted a prospective study to determine the most characteristics ultrasonic feature suggestive of metastatic node. Material and Methods: A preliminary study based on feasibility was planned on twenty five patients with squamous cell carcinoma of tongue (T1,T2) and N0 neck underwent ultrasonography of neck. The results of each ultrasonic parameters (size, shape, echogenicity, margin and hilum) for suspicion were analysed. Pathologic evaluation of surgical resected neck specimen served as the reference standard. Results: USG yielded sensitivity and specificity by size, by morphology, either size or morphology are 50.0% and 87.5%, 75.0% and 87.5, 75.0 and 83.3% respectively. Morphology alone has highest negative predictive value (NPV:91.3%) with accuracy of 84.3%. Conclusion: Morphology of the lymph node had highest sensitivity and specificity with highest negative predictive value correlating with its metastatic nature.

Keywords: Early tongue cancer; Occult lymph node; Oral cancer; Ultrasonography neck.