Edmund Lawrence Dubois (1923-1985)

Abstract

In the year 1950, Edmund Dubois was asked to evaluate eight patients who had positive results from a new blood test known as the LE cell prep. This was the springboard for him to launch a career that elucidated new and unique insights into the pathogenesis, clinical presentation, laboratory testing, and treatment of systemic lupus erythematosus. Between 1950 and 1985, he treated more than 2000 patients with the disorder and wrote the principal textbook on the subject.

Keywords: Cedars-Sinai Medical Center; LE cell prep; Lupus; Systemic lupus erythematosus; University of Southern California.