Comparison of pathological findings and accumulation of fluorin-18 fluorodeoxyglucose on positron emission tomography/computed tomography: A case of relapsing polychondritis

Hirokazu Tokuyasu; Haruka Watanabe; Yuriko Sueda; Hiromitsu Sakai; Natsumi Omura-Tanaka; Kenichirou Nakajima; Satoru Nakamatsu; Chika Esumi; Akira Yamasaki

doi:10.1016/j.rmcr.2023.101937

Comparison of pathological findings and accumulation of fluorin-18 fluorodeoxyglucose on positron emission tomography/computed tomography: A case of relapsing polychondritis

Respir Med Case Rep. 2023 Oct 21:46:101937. doi: 10.1016/j.rmcr.2023.101937. eCollection 2023.

Authors

Hirokazu Tokuyasu¹, Haruka Watanabe¹, Yuriko Sueda¹, Hiromitsu Sakai¹, Natsumi Omura-Tanaka¹, Kenichirou Nakajima², Satoru Nakamatsu³, Chika Esumi⁴, Akira Yamasaki⁵

Affiliations

¹ Department of Respiratory Medicine, Matsue Red Cross Hospital, Shimane, Japan.
² Department of Otolaryngology, Matsue Red Cross Hospital, Shimane, Japan.
³ Department of Radiology, Matsue Red Cross Hospital, Shimane, Japan.
⁴ Department of Pathology, Matsue Red Cross Hospital, Shimane, Japan.
⁵ Division of Respiratory Medicine and Rheumatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Faculty of Medicine, Tottori University, Yonago, Japan.

Abstract

A 70-year-old woman with a hoarse voice and dry cough was referred to our hospital. Positron emission tomography/computed tomography showed abnormal accumulation of fluorine-18 fluorodeoxyglucose (FDG) at the nasal septum, larynx, trachea, bronchus, and costal cartilages. The maximum standard uptake values of FDG accumulation in the nasal septum and costal cartilage were similar. Biopsies of the nasal septum and costal cartilage were performed. The patient was diagnosed with relapsing polychondritis (RP) based on the clinical features and pathological findings. Histopathological examination revealed progressive initial RP findings. The disease progression was different, even with the same FDG accumulation.

Keywords: Fluorine-18 fluorodeoxyglucose; Histopathological examination; Positron emission tomography/computed tomography; Prednisolone; Relapsing polychondritis.

Publication types

Case Reports