Diagnosing familial platelet disorder with predisposition to myeloid malignancy: Lessons learned from a germline whole-gene deletion of RUNX1

Int J Lab Hematol. 2024 Feb;46(1):203-206. doi: 10.1111/ijlh.14199. Epub 2023 Nov 12.

Authors

John A Cliburn¹, Jann C Uy², Sharon Swift³, Jane L Liesveld³, M Anwar Iqbal², Audrey N Jajosky², Michael W Becker³

Affiliations

¹ School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.
² Department of Pathology, Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA.
³ Department of Medicine, Division of Hematology and Oncology, University of Rochester Medical Center, Wilmot Cancer Institute, Rochester, New York, USA.

PMID: 37953439
DOI: 10.1111/ijlh.14199

No abstract available

Publication types

Letter

MeSH terms

Blood Platelet Disorders* / diagnosis
Blood Platelet Disorders* / genetics
Blood Platelets
Core Binding Factor Alpha 2 Subunit / genetics
Disease Susceptibility
Gene Deletion
Genetic Predisposition to Disease
Germ Cells
Humans
Leukemia, Myeloid, Acute* / genetics
Neoplasms*

Substances

Core Binding Factor Alpha 2 Subunit
RUNX1 protein, human