Application of contrast-enhanced ultrasound in renal space-occupying lesion puncture biopsy

BMC Med Imaging. 2023 Nov 8;23(1):178. doi: 10.1186/s12880-023-01137-9.

Abstract

Objective: The purpose of this study was to investigate the utility of contrast-enhanced ultrasound (CEUS) in percutaneous renal space-occupying lesion puncture biopsy.

Methods: Ultrasound (US)-guided percutaneous needle biopsies were performed on 55 patients with renal space-occupying lesions, and the results were analyzed retrospectively. The US group included 36 patients receiving conventional US, and the contrast-enhanced ultrasound (CEUS) group included 22 patients, including 19 patients receiving CEUS directly and 3 patients receiving additional enhanced ultrasound due to the first conventional ultrasound puncture failure. The relevant data were subjected to statistical analysis.

Results: The results of this study showed that the successful rate of obtaining effective tissue (100% vs. 75%) and the puncture accuracy (100% vs. 88.89%) in CEUS group were significantly higher than those in US group (P < 0.05). CEUS-guided puncture biopsy of renal mass, especially in the case of urothelial carcinoma of the renal pelvis, outperforms conventional ultrasound, and the difference was statistically significant (P < 0.05).

Conclusion: Percutaneous renal space-occupying lesion puncture biopsies aided by CEUS yield more effective tissue and improved puncture accuracy.

Keywords: Biopsy; Contrast-enhanced ultrasound; Puncture; Renal tumors; Ultrasound.

MeSH terms

  • Biopsy
  • Biopsy, Needle
  • Carcinoma, Transitional Cell*
  • Contrast Media
  • Humans
  • Punctures
  • Retrospective Studies
  • Ultrasonography
  • Urinary Bladder Neoplasms*

Substances

  • Contrast Media