MeCP2 is the protector of epigenome integrity, membrane-less nuclear architecture, and stability of chromatin assembly

Epigenomics. 2023 Oct;15(20):1027-1031. doi: 10.2217/epi-2023-0310. Epub 2023 Nov 8.

Abstract

Tweetable abstract MeCP2 is an epigenetic factor with global impact in epigenome integrity, membrane-less nuclear architecture, and chromatin stability. Our Editorial covers recent advances on these important topics.

Keywords: Chromatin assembly; DNA methylation; MeCP2; epigenomics; nuclear architecture.

Publication types

  • Editorial

MeSH terms

  • Chromatin / genetics
  • Chromatin Assembly and Disassembly*
  • DNA Methylation
  • Epigenome*
  • Epigenomics
  • Humans
  • Methyl-CpG-Binding Protein 2* / genetics
  • Methyl-CpG-Binding Protein 2* / metabolism

Substances

  • Chromatin
  • Methyl-CpG-Binding Protein 2