Development of calculation tool for iodine 131 biodistribution depending on the aerosol particle distribution

Abstract

Radiation damage to tissues depends on radiation exposure levels. Therefore, we have studied accurate estimations of radiation exposure levels so far. Recently, we developed a tool that can calculate the respiratory tract deposition of radionuclides based on polydisperse particle size distribution. As a next step, there is a need for a new calculation tool for the biodistribution of radionuclides because a fraction of the radionuclides deposited in the respiratory tract is absorbed into the body. In this study, a calculation tool for iodine 131 biodistribution depending on aerosol size distribution was developed. The developed tool in this study is used with the former tool.