Sarcoid optic neuropathy

Pract Neurol. 2024 Mar 19;24(2):141-143. doi: 10.1136/pn-2023-003939.

Abstract

A 45-year-old woman presented with sudden complete vision loss in her left eye and retroorbital pain worsened by eye movements. A previous milder episode of vision loss had occurred in the same eye 1 year before, with complete recovery after high-dose intravenous methylprednisolone. She had no light perception in the left eye with a swollen optic disc, but with a normal right optic disc. There were no systemic manifestations or infections. MR scan of the brain showed extensive enlargement and enhancement of the left optic nerve and optic chiasm. After excluding infections and autoimmune markers, a left optic nerve biopsy confirmed non-caseating granulomas, leading to a diagnosis of neurosarcoidosis.

Keywords: NEUROOPHTHALMOLOGY; NEUROPATHOLOGY; ONCOLOGY.

Publication types

  • Case Reports

MeSH terms

  • Blindness
  • Central Nervous System Diseases*
  • Female
  • Humans
  • Middle Aged
  • Neuritis* / pathology
  • Optic Nerve / pathology
  • Optic Nerve Diseases* / diagnostic imaging
  • Optic Nerve Diseases* / etiology
  • Sarcoidosis* / complications
  • Sarcoidosis* / diagnostic imaging

Supplementary concepts

  • Neurosarcoidosis