Bile duct hamartoma in a dog

Dongsheng Mao; Xudong Song; Dexing Ma; Shouping Hu; Zhuo Zhang; Jingfei Wang; Xijun He

doi:10.1016/j.jcpa.2023.10.003

Bile duct hamartoma in a dog

J Comp Pathol. 2023 Nov:207:45-49. doi: 10.1016/j.jcpa.2023.10.003. Epub 2023 Nov 4.

Authors

Dongsheng Mao¹, Xudong Song², Dexing Ma², Shouping Hu¹, Zhuo Zhang¹, Jingfei Wang¹, Xijun He³

Affiliations

¹ State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 678 Haping Road, Xiangfang District, Harbin, 150001, China.
² Northeast Agricultural University, 600 Changjiang Road, Xiangfang District, Harbin, 150006, China.
³ State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 678 Haping Road, Xiangfang District, Harbin, 150001, China. Electronic address: hexijun@caas.cn.

PMID: 37931467
DOI: 10.1016/j.jcpa.2023.10.003

Abstract

An 11-year-old female Collie presented with a significantly increased abdominal circumference. Computed tomography of the abdomen revealed that the left lateral lobe of the liver contained a large mass, which was excised via laparotomy. Histologically, many small, dilated, cystic luminal structures were anastomosed and connected to a net-like structure. Immunohistochemistry revealed cytokeratin 19-immunopositive areas, representing bile duct structures in the cystic lumen. Based on these results, the tumour was diagnosed as a bile duct hamartoma. To our knowledge, this is the first report of a bile duct hamartoma in a dog.

Keywords: bile duct; dog; hamartoma; liver; von Meyenburg complex-like tumour.

Publication types

Case Reports

MeSH terms

Animals
Bile Ducts / pathology
Bile Ducts, Intrahepatic / pathology
Dog Diseases* / pathology
Dogs
Female
Hamartoma* / diagnosis
Hamartoma* / veterinary
Liver Neoplasms* / veterinary