[Bronchial diseases and heroin use. A systematic review]

Rev Mal Respir. 2023 Nov-Dec;40(9-10):783-809. doi: 10.1016/j.rmr.2023.09.006. Epub 2023 Nov 2.
[Article in French]

Abstract

Introduction: Heroin use can cause respiratory complications including asthma, chronic obstructive pulmonary disease (COPD) and bronchiectasis (BD).

Objectives: A general review of the literature presenting the data on the relationships between heroin consumption and bronchial complications, while underlining the difficulties of diagnosis and management.

Documentary sources: Medline, 1980-2022, keywords "asthma" or "bronchospasm" or "COPD" or "bronchiectasis" and "heroin" or "opiate" or "opiates", with limits pertaining to "Title/Abstract". Concerning asthma, 26 studies were included, as were 16 for COPD and 5 for BD.

Results: Asthma and COPD are more prevalent among heroin addicts, who are less compliant than other patients with their treatment. The authors found a positive association between frequency of asthma exacerbations, admission to intensive care and heroin inhalation. Late diagnosis of COPD worsens the course of the disease; emphysema and BD are poor prognostic factors.

Conclusion: Bronchial diseases in heroin users can be identified by means of respiratory function exploration and chest CT scans. These tests should be performed frequently in view of optimizing their care, which includes their weaning themselves from addictive substances.

Keywords: Asthma; Asthme; BPCO; Bronchectasies; Bronchiectasis; COPD; Emphysema; Emphysème; Heroin; Héroïne; Opiacés; Opiates.

Publication types

  • Systematic Review
  • English Abstract
  • Review

MeSH terms

  • Asthma* / etiology
  • Bronchiectasis* / complications
  • Heroin
  • Humans
  • Pulmonary Disease, Chronic Obstructive* / diagnosis
  • Pulmonary Disease, Chronic Obstructive* / epidemiology
  • Pulmonary Disease, Chronic Obstructive* / etiology
  • Pulmonary Emphysema* / complications

Substances

  • Heroin