If the Patient Does Not Take the Medication, It Will Not Work

Iván Sánchez Fernández; Adriana Ulate-Campos

doi:10.1016/j.spen.2023.101079

If the Patient Does Not Take the Medication, It Will Not Work

Semin Pediatr Neurol. 2023 Oct:47:101079. doi: 10.1016/j.spen.2023.101079. Epub 2023 Sep 7.

Authors

Iván Sánchez Fernández¹, Adriana Ulate-Campos²

Affiliations

¹ Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: ivan.sanchezfernandez@childrens.harvard.edu.
² National Children's Hospital Dr. Carlos Saenz Herrera, San José, Costa Rica.

PMID: 37919036
DOI: 10.1016/j.spen.2023.101079

Abstract

AN UNWANTED EFFECT OF ANTIEPILEPTIC DRUGS IN CHILDREN: Adriana Ulate-Campos, Iván Sánchez Fernández Seminars in Pediatric Neurology Volume 24, Issue 4, November 2017, Pages 320-330 Epilepsy is one of the most common neurological disorders and, despite optimally chosen and dosed antiepileptic drugs (AEDs), approximately 20%-30% of patients will continue to have seizures. Behavior and cognition are negatively impacted by seizures, but AEDs are also a major contributor to behavioral and cognitive deficits. However, the cognitive and behavioral effect of AEDs in children is insufficiently emphasized in the literature. This review summarizes the cognitive and behavioral effects of AEDs in the pediatric population with the objective of helping pediatricians and pediatric neurologists to select the AEDs with the best profile for their individual patient's needs.

Publication types

Review

MeSH terms

Anticonvulsants / adverse effects
Child
Cognition Disorders*
Comorbidity
Epilepsy* / drug therapy
Epilepsy* / psychology
Humans
Seizures / drug therapy

Substances

Anticonvulsants