Hepatitis A outbreak in a refugee shelter in Kiel, northern Germany

J Med Virol. 2023 Nov;95(11):e29185. doi: 10.1002/jmv.29185.

Abstract

In the spring of 2023, three Ukrainian war refugees from a municipal community shelter and a volunteer caregiver at an affiliated daycare center in Kiel, Germany, were diagnosed with infectious jaundice attributable to a single hepatitis A virus (HAV) subgenotype IA strain. Similar HAV sequences have been observed in Germany and other European countries for several years. One refugee and the volunteer required hospitalization. Four children were asymptomatically infected but excreted high levels of HAV ribonucleic acid in the stool. The infections were probably acquired in Germany, but a source could not be determined. The outbreak was contained through vaccination, increased hygiene, and education. The existing HAV vaccination recommendation for refugee shelter staff and volunteers should be consistently implemented.

Keywords: HAV subgenotype IA; acute viral hepatitis; refugees; vaccination recommendation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Disease Outbreaks
  • Genotype
  • Germany / epidemiology
  • Hepatitis A virus* / genetics
  • Hepatitis A* / epidemiology
  • Humans
  • Phylogeny
  • RNA, Viral / genetics
  • Refugees*

Substances

  • RNA, Viral