Human N-CAM gene: mapping to chromosome 11 by analysis of somatic cell hybrids with mouse and human cDNA probes

Brain Res. 1986 Nov;387(2):197-200. doi: 10.1016/0169-328x(86)90012-4.

Abstract

We have used mouse and human cDNA probes to map the chromosomal position of the N-CAM gene in the human genome. Southern analysis of DNA isolated from a panel of mouse-human somatic cell hybrids has assigned the N-CAM gene to chromosome 11. This assignment was found with both mouse and human N-CAM cDNAs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Surface / genetics*
  • Cell Adhesion Molecules
  • Cell Line
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 11 / analysis*
  • DNA
  • Electrophoresis, Agar Gel
  • Humans
  • Hybrid Cells / analysis
  • Mice
  • Muscles / analysis

Substances

  • Antigens, Surface
  • Cell Adhesion Molecules
  • DNA