Occupational heat stress recommendations attenuate AKI risk compared with a work–rest ratio–matched positive control scenario.
Heat-induced AKI risk is strongly related to peak core temperature.
The peak change in serum creatinine largely paralleled peak changes in urinary [insulin-like growth factor-binding protein 7·tissue inhibitor metalloproteinase 2].
Trial registration: ClinicalTrials.gov NCT04767347.