Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review

Cureus. 2023 Sep 29;15(9):e46219. doi: 10.7759/cureus.46219. eCollection 2023 Sep.

Abstract

Prostate cancer has an indolent progression course and commonly metastasizes to the vertebrae bone and regional lymph nodes. We report a patient with prostate cancer who has developed cutaneous metastases in multiple regions, including the right infraclavicular and abdominal area, as well as the left supraclavicular region. It presented as isolated, prominent nodules that were microscopically proven to be of prostate adenocarcinoma when biopsied. This rare presentation is a marker of an advanced disease course with a poor prognosis in castrate-resistant prostate cancer. Thorough clinical examination to rule out metastasis from the prostate and other dermatological conditions is paramount as well as ensuring early detection and optimizing patient outcomes.

Keywords: adenocarcinoma; cutaneous metastasis; oncology; prostate cancer; prostate-specific antigen (psa).

Publication types

  • Case Reports