Updates to the Management of Gorham-Stout Disease and Osseous Vascular Lesions in the Head and Neck

Andrea B Burke; Chao Dong; Srinivasa R Chandra

doi:10.1016/j.coms.2023.09.004

Updates to the Management of Gorham-Stout Disease and Osseous Vascular Lesions in the Head and Neck

Oral Maxillofac Surg Clin North Am. 2024 Feb;36(1):93-102. doi: 10.1016/j.coms.2023.09.004. Epub 2023 Oct 29.

Authors

Andrea B Burke¹, Chao Dong², Srinivasa R Chandra³

Affiliations

¹ Oral and Maxillofacial Surgery, University of Washington School of Dentistry, 1959 Northeast Pacific Street, Box 357134, Seattle, WA 98195-7134, USA. Electronic address: abburke@uw.edu.
² University of Washington School of Dentistry.
³ Oral & Maxillofacial Surgery-Head Neck Oncology/Microvascular Reconstruction, Oregon Health & Science University.

PMID: 37903662
DOI: 10.1016/j.coms.2023.09.004

Abstract

Osseous vascular anomalies can be characterized as vascular tumors or malformations. Classification is vital for prognosis and treatment. Much remains unknown about conditions such as Gorham-Stout disease. Treatments target the proposed genetic pathways such as PI3KCA/AKT/mTOR pathway.

Keywords: Disappearing bone; Epithelioid hemangioma; Gorham–Stout disease; Hemangioma; Intraosseous hemangioma; Lymphangiomatosis; Pseudomyogenic hemangioendothelioma; Vascular tumor.

Publication types

Review

MeSH terms

Humans
Neck
Osteolysis, Essential* / diagnosis
Osteolysis, Essential* / therapy