12-Month Efficacy of Advanced Hybrid Closed-Loop System in Adult Type 1 Diabetes Patients

Diabetes Technol Ther. 2024 Feb;26(2):130-135. doi: 10.1089/dia.2023.0319. Epub 2023 Nov 14.

Abstract

Automated insulin delivery (AID) systems have improved glycemic control in individuals with type 1 diabetes (T1D). The "advanced hybrid closed loop" (AHCL) stands out as the most recent development in AID systems for T1D management. In a real-world clinical environment, we retrospectively evaluated the AHCL MiniMed™ 780G system's effectiveness to achieve and sustain glycemic control over a 12-month period in 22 adult T1D subjects. Within just 14 days of activating the automatic mode, the AHCL MiniMed 780G system showed rapid improvement in glycemic control, which persisted for 12 months. These findings underscore the effectiveness of AHCL systems in achieving and preserving optimal glycemic control in adults with T1D over a very long follow-up.

Keywords: Advanced hybrid closed loop; Insulin therapy; Technology; Type 1 diabetes.

MeSH terms

  • Adult
  • Blood Glucose
  • Diabetes Mellitus, Type 1* / drug therapy
  • Glycemic Control
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Pancreas, Artificial*
  • Retrospective Studies

Substances

  • Insulin
  • Blood Glucose
  • Hypoglycemic Agents