Thixotropic Hydrogels Based on Laponite® and Cucurbituril for Delivery of Lipophilic Drug Molecules

Chempluschem. 2024 Jan;89(1):e202300592. doi: 10.1002/cplu.202300592. Epub 2023 Oct 30.

Abstract

Invited for this month's cover are the collaborating groups of Prof. Serena Riela at University of Catania, Prof. César Viseras at University of Granada and Dr. Ignacio Sainz-Diaz at Instituto Andaluz de Ciencias de la Tierra. The cover picture shows the possible application of the developed system. In particular, flufenamic acid, anti-inflammatory and anti-pyretic drug, was complexed into cucurbituril cavity and the supramolecular system obtained was used as filler for laponite® hydrogel for its topical delivery. More information can be found in the Research Article by Viseras-Iborra, Riela, and co-workers.

MeSH terms

  • Flufenamic Acid*
  • Humans
  • Hydrogels
  • Macrocyclic Compounds*
  • Silicates*

Substances

  • laponite
  • Flufenamic Acid
  • Hydrogels
  • Macrocyclic Compounds
  • Silicates