The Effect of Bariatric Surgery on Patients with Heart Failure: a Systematic Review and Meta-analysis

Ali Esparham; Ali Mehri; Hooman Hadian; Maryam Taheri; Hengameh Anari Moghadam; Armin Kalantari; Michael J Fogli; Zhamak Khorgami

doi:10.1007/s11695-023-06898-4

The Effect of Bariatric Surgery on Patients with Heart Failure: a Systematic Review and Meta-analysis

Obes Surg. 2023 Dec;33(12):4125-4136. doi: 10.1007/s11695-023-06898-4. Epub 2023 Oct 28.

Authors

Ali Esparham¹, Ali Mehri², Hooman Hadian³, Maryam Taheri⁴, Hengameh Anari Moghadam¹, Armin Kalantari⁵, Michael J Fogli^{4

6}, Zhamak Khorgami^{7

8}

Affiliations

¹ School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
² Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
³ Heshmatieh Hospital, Naieen City, Iran.
⁴ Department of Cardiology, Ascension St. John Medical Center, Tulsa, OK, USA.
⁵ Department of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, USA.
⁶ Department of Internal Medicine, University of Oklahoma School of Community Medicine, Tulsa, Oklahoma, USA.
⁷ Department of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, USA. zhamak-khorgami@ouhsc.edu.
⁸ Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. zhamak-khorgami@ouhsc.edu.

PMID: 37897639
DOI: 10.1007/s11695-023-06898-4

Abstract

The current study aims to evaluate the effect of bariatric metabolic surgery (BMS) on the New York Heart Association (NYHA) class and left ventricular ejection fraction (LVEF) in patients with diagnosed heart failure (HF). Fourteen related articles with 217 patients were included in the final analysis. LVEF significantly improved after BMS in patients with HF with a mean difference of 7.78% (CI 95%: 3.72, 11.84, I² = 83.75, p-value < 0.001). Also, the NYHA class significantly decreased after BMS with a mean difference of - 0.40 (CI 95%: - 0.62, - 0.19, I²: 47.03, p-value < 0.001). A total of 27 patients with obesity and HF were listed for cardiac transplantation after BMS. Of those, 20 patients successfully underwent heart transplantation after BMS.

Keywords: Bariatric surgery; Cardiovascular disease; Heart failure; Heart transplant; Metabolic surgery; Obesity.

Publication types

Meta-Analysis
Systematic Review
Review

MeSH terms

Bariatric Surgery* / adverse effects
Heart Failure* / surgery
Humans
Obesity, Morbid* / surgery
Stroke Volume
Ventricular Function, Left