Ergot Alkaloids on Cereals and Seeds: Analytical Methods, Occurrence, and Future Perspectives

Molecules. 2023 Oct 23;28(20):7233. doi: 10.3390/molecules28207233.

Abstract

Ergot alkaloids are secondary metabolites resulting from fungi of the genus Claviceps that have proven to be highly toxic. These mycotoxins commonly infect cereal crops such as wheat, rye, barley, and oats. Due to the increase worldwide consumption of cereal and cereal-based products, the presence of ergot alkaloids in food presents a concern for human safety. For this reason, it is essential to develop several analytical methods that allow the detection of these toxic compounds. This review compiles and discusses the most relevant studies and methods used in the detection and quantification of ergot alkaloids. Moreover, the decontamination techniques are also addressed, with special attention to sorting, cleaning, frying, baking, peeling, and ammonization methods, as they are the only ones already applied to ergot alkaloids.

Keywords: analytical methods; cereals; decontamination; ergot alkaloids; mycotoxins.

Publication types

  • Review

MeSH terms

  • Claviceps*
  • Dopamine Agonists
  • Edible Grain / chemistry
  • Ergot Alkaloids*
  • Food Contamination / analysis
  • Heterocyclic Compounds, 4 or More Rings
  • Humans
  • Mycotoxins* / analysis

Substances

  • Ergot Alkaloids
  • Mycotoxins
  • Heterocyclic Compounds, 4 or More Rings
  • Dopamine Agonists

Grants and funding

The work was supported by UIDB/00211/2020 with funding from FCT/MCTES through national funds. A.R.S.M. would like to thank to FCT for her fellowship (2023.04705.BDANA).