Current and Potential Applications of Monoterpenes and Their Derivatives in Oral Health Care

Molecules. 2023 Oct 19;28(20):7178. doi: 10.3390/molecules28207178.

Abstract

Plant products have been employed in medicine for centuries. As the world becomes more health-conscious, there is a growing interest in natural and minimally processed products for oral health care. This has led to an increase in research into the bioactive compounds found in plant products, particularly monoterpenes. Monoterpenes are known to have beneficial biological properties, but the specific mechanisms by which they exert their effects are not yet fully understood. Despite this, some monoterpenes are already being used in oral health care. For example, thymol, which has antibacterial properties, is an ingredient in varnish used for caries prevention. In addition to this, monoterpenes have also demonstrated antifungal, antiviral, and anti-inflammatory properties, making them versatile for various applications. As research continues, there is potential for even more discoveries regarding the benefits of monoterpenes in oral health care. This narrative literature review gives an overview of the biological properties and current and potential applications of selected monoterpenes and their derivatives in oral health care. These compounds demonstrate promising potential for future medical development, and their applications in future research are expected to expand.

Keywords: dentistry; monoterpene; monoterpenoid; oral health; plant oil; plant product; terpene; volatile oil.

Publication types

  • Review

MeSH terms

  • Antifungal Agents
  • Delivery of Health Care
  • Monoterpenes* / pharmacology
  • Monoterpenes* / therapeutic use
  • Oils, Volatile*
  • Thymol

Substances

  • Monoterpenes
  • Oils, Volatile
  • Thymol
  • Antifungal Agents