Modular Neural Networks for Osteoporosis Detection in Mandibular Cone-Beam Computed Tomography Scans

Tomography. 2023 Sep 22;9(5):1772-1786. doi: 10.3390/tomography9050141.

Abstract

In this technical note, we examine the capabilities of deep convolutional neural networks (DCNNs) for diagnosing osteoporosis through cone-beam computed tomography (CBCT) scans of the mandible. The evaluation was conducted using 188 patients' mandibular CBCT images utilizing DCNN models built on the ResNet-101 framework. We adopted a segmented three-phase method to assess osteoporosis. Stage 1 focused on mandibular bone slice identification, Stage 2 pinpointed the coordinates for mandibular bone cross-sectional views, and Stage 3 computed the mandibular bone's thickness, highlighting osteoporotic variances. The procedure, built using ResNet-101 networks, showcased efficacy in osteoporosis detection using CBCT scans: Stage 1 achieved a remarkable 98.85% training accuracy, Stage 2 minimized L1 loss to a mere 1.02 pixels, and the last stage's bone thickness computation algorithm reported a mean squared error of 0.8377. These findings underline the significant potential of AI in osteoporosis identification and its promise for enhanced medical care. The compartmentalized method endorses a sturdier DCNN training and heightened model transparency. Moreover, the outcomes illustrate the efficacy of a modular transfer learning method for osteoporosis detection, even when relying on limited mandibular CBCT datasets. The methodology given is accompanied by the source code available on GitLab.

Keywords: CBCT; artificial intelligence; convolutional neural network; deep learning; dentistry; osteoporosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cone-Beam Computed Tomography / methods
  • Cross-Sectional Studies
  • Humans
  • Mandible / diagnostic imaging
  • Neural Networks, Computer
  • Osteoporosis* / diagnostic imaging

Grants and funding

This research and APC were funded by the Latvian Council of Science under the project “A Deep Learning Approach for Osteoporosis Identification using Cone-beam Computed Tomography”, grant number lzp-2021/1-0031.