A single dietary factor, daily consumption of a fermented beverage, can modulate the gut bacteria and fecal metabolites within the same ethnic community

mSystems. 2023 Dec 21;8(6):e0074523. doi: 10.1128/msystems.00745-23. Epub 2023 Oct 26.

Abstract

Our study investigated how a traditional drink called Apong, made from fermented rice, affects the gut and health of the Mishing community in India. We compared two groups of people who drink Apong to a group of people who do not drink it. To accomplish this, we studied the gut bacteria, fecal metabolites, and blood samples of the participants. It was found that the people who drank Apong had higher blood pressure but lower blood sugar and protein levels than people who did not drink it. We also found that the gut microbiome composition of people who drank Apong was different from those who did not drink it. Moreover, people who drank Apong had lower levels of isovaleric acid in their feces. Overall, this study shows that a traditional drink like Apong can affect the gut bacteria of a community.

Keywords: alcoholic beverage; fecal metabolites; fermented beverage; gut microbiome; short-chain fatty acids.

MeSH terms

  • Bacteria
  • Feces / microbiology
  • Fermented Beverages
  • Gastrointestinal Microbiome*
  • Humans
  • Hypertension*