Research status and prospect on the mechanisms of acupuncture and moxibustion treatment for constipation of Parkinson's disease

Zhen Ci Yan Jiu. 2023 Oct 25;48(10):1055-1061. doi: 10.13702/j.1000-0607.20230276.
[Article in English, Chinese]

Abstract
in English, Chinese

Constipation may accelerate the progression of Parkinson's disease (PD). The quality of life in PD patients can be significantly improved when constipation is treated, hence the disease progression may be delayed. At present, the mechanism research is still at the initial stage for acupuncture in treatment of PD, focusing on neurohumoral factors, intestinal flora, bacterial fermentation products and intestinal inflammation； and there are the problems such as single intervention, thinking limitation and insufficient cooperation among disciplines. This paper systematically reviews the mechanism research progress of acupuncture for the treatment of constipation in PD so as to provide the references for the subsequent studies.

帕金森病（PD）便秘一定程度上可加速PD的进展。治疗便秘能够明显改善PD患者的生活质量，并可能延缓PD的进展。目前，针灸治疗PD便秘的机制研究尚处于起步阶段，主要围绕神经体液因子、肠道菌群及细菌发酵产物、肠道炎性反应等方面进行研究，存在研究干预方法单一、研究思维局限、学科间合作不足等问题。本文通过系统梳理针灸治疗PD便秘的机制研究进展，以期为后续研究提供参考。.

Keywords: Acupuncture-moxibustion; Constipation; Parkinson’s disease; Progress of mechanism research.

MeSH terms

  • Acupuncture Therapy*
  • Constipation / therapy
  • Humans
  • Moxibustion*
  • Parkinson Disease* / complications
  • Parkinson Disease* / therapy
  • Quality of Life