Screening for haemoglobin disorders: One size may not fit all

Lisa M Shook; Russell E Ware

doi:10.1111/bjh.19160

Screening for haemoglobin disorders: One size may not fit all

Br J Haematol. 2024 Jan;204(1):26-28. doi: 10.1111/bjh.19160. Epub 2023 Oct 25.

Authors

Lisa M Shook^{1

2

3}, Russell E Ware^{1

2

3

4}

Affiliations

¹ Division of Hematology, Department of Pediatrics, Cincinnati Children's Hospital Medical Centre, Cincinnati, Ohio, USA.
² Comprehensive Sickle Cell Centre, Cincinnati Children's Hospital Medical Centre, Cincinnati, Ohio, USA.
³ Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
⁴ Global Health Centre, Cincinnati Children's Hospital Medical Centre, Cincinnati, Ohio, USA.

PMID: 37877454
DOI: 10.1111/bjh.19160

Abstract

Accurate laboratory screening for sickle cell disease and other haemoglobin disorders is expanding worldwide. Two new reports describe different methods and strategies for screening in Mali and Denmark, respectively, and their encouraging results suggest that countries should tailor their screening programmes according to local needs, resources and opportunities. Commentary on: Guindo et al. Potential for a large-scale newborn screening strategy for sickle cell disease in Mali: a comparative diagnostic performance study of two rapid diagnostic tests (SickleScan® and HemotypeSC®) on cord blood. Br J Haematol 2024;204:337-345 and Gravholt et al. The Danish national haemoglobinopathy screening programme: report from 16 years of screening in a low-prevalence, non-endemic region. Br J Haematol 2024;204:329-336.

Keywords: haemoglobin disorders; laboratory screening; sickle cell disease.

Publication types

Comment

MeSH terms

Anemia, Sickle Cell* / diagnosis
Anemia, Sickle Cell* / epidemiology
Fetal Blood
Hemoglobinopathies* / diagnosis
Hemoglobinopathies* / epidemiology
Hemoglobins
Humans
Infant, Newborn
Neonatal Screening / methods

Substances

Hemoglobins