Neuroscience: Building better cognition through smell

Donald A Wilson; Regina M Sullivan

doi:10.1016/j.cub.2023.09.030

Neuroscience: Building better cognition through smell

Curr Biol. 2023 Oct 23;33(20):R1049-R1051. doi: 10.1016/j.cub.2023.09.030.

Authors

Donald A Wilson¹, Regina M Sullivan²

Affiliations

¹ Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA; Department of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY 10016, USA. Electronic address: donald.wilson@nyulangone.org.
² Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA; Department of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY 10016, USA.

PMID: 37875078
DOI: 10.1016/j.cub.2023.09.030

Abstract

Developmental neural activity organizes sensory system development. New evidence in mice suggests postnatal olfactory bulb activity also modulates development of the structure and function of hippocampal-cortical circuits. Reducing cell-specific olfactory bulb output during an infant sensitive period impairs later-life cognition.

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MeSH terms

Animals
Cognition
Hippocampus
Humans
Mice
Neurosciences*
Odorants
Olfactory Bulb
Smell*