Site-specifically radiolabeled nanobodies for imaging blood-brain barrier penetration and targeting in the brain

Abstract

Nanobodies (Nbs) hold significant potential in molecular imaging due to their unique characteristics. However, there are challenges to overcome when it comes to brain imaging. To address these obstacles, collaborative efforts and interdisciplinary research are needed. This article aims to raise awareness and encourage collaboration among researchers from various fields to find solutions for effective brain imaging using Nbs. By fostering cooperation and knowledge sharing, we can make progress in overcoming the existing limitations and pave the way for improved molecular imaging techniques in the future.

Keywords: BBB penetration; brain disorder; molecular imaging; nanobody; site-specific labeling.