Admix-kit: An Integrated Toolkit and Pipeline for Genetic Analyses of Admixed Populations

bioRxiv [Preprint]. 2023 Oct 2:2023.09.30.560263. doi: 10.1101/2023.09.30.560263.

Abstract

Admixed populations, with their unique and diverse genetic backgrounds, are often underrepresented in genetic studies. This oversight not only limits our understanding but also exacerbates existing health disparities. One major barrier has been the lack of efficient tools tailored for the special challenges of genetic study of admixed populations. Here, we present admix-kit, an integrated toolkit and pipeline for genetic analyses of admixed populations. Admix-kit implements a suite of methods to facilitate genotype and phenotype simulation, association testing, genetic architecture inference, and polygenic scoring in admixed populations.

Publication types

  • Preprint