International AIDS society conference 2023 summary

Abstract

Aim: This article summarizes key research presented at the International AIDS Society (IAS) Conference in Brisbane, held in July 2023.

Co-morbidities: The REPRIEVE Trial as a conference highlight, demonstrating significantly fewer major cardiovascular events amongst people with HIV who were randomized to pitavastatin compared to placebo. Key data on weight, hypertension and incident diabetes are also summarized.

Antiretroviral therapy: Novel data on doravirine and islatravir are described as are trials demonstrating efficacy dolutegravir/lamivudine first-line in people without baseline resistance testing and in suppressed switch amongst people with historic lamivudine resistance.

Hiv cure: The sixth case of HIV cure secondary to stem cell transplantation is summarized, as are new insights into the central nervous system as an HIV reservoir.

Keywords: HIV; IAS; antiretroviral; co-morbidities; conference; cure.