Anaesthetic management of people with multiple sclerosis

N Dubuisson; O de Maere d'Aertrijcke; M Marta; S Gnanapavan; B Turner; D Baker; K Schmierer; G Giovannoni; V Verma; M-A Docquier

doi:10.1016/j.msard.2023.105045

Anaesthetic management of people with multiple sclerosis

Mult Scler Relat Disord. 2023 Dec:80:105045. doi: 10.1016/j.msard.2023.105045. Epub 2023 Oct 11.

Authors

N Dubuisson¹, O de Maere d'Aertrijcke², M Marta³, S Gnanapavan³, B Turner³, D Baker⁴, K Schmierer³, G Giovannoni³, V Verma⁵, M-A Docquier²

Affiliations

¹ Faculty of Medicine and Dentistry, Blizard Institute (Neuroscience), Queen Mary University London, 4 Newark Street, London E1 2AT, UK; Neuromuscular Reference Center, Department of Neurology, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, Brussels 1200, Belgium. Electronic address: Nicolas.j.dubuisson@uclouvain.be.
² Department of Anesthesia and Perioperative Medicine, Cliniques Universitaires Saint-Luc, St Luc Hospital, Avenue Hippocrate 10, Brussels 1200, Belgium.
³ Faculty of Medicine and Dentistry, Blizard Institute (Neuroscience), Queen Mary University London, 4 Newark Street, London E1 2AT, UK; Clinical Board Medicine (Neuroscience), The Royal London Hospital, Barts Health NHS Trust, London, UK.
⁴ Faculty of Medicine and Dentistry, Blizard Institute (Neuroscience), Queen Mary University London, 4 Newark Street, London E1 2AT, UK.
⁵ Department of Anesthesia, Royal London Hospital, Barts Health NHS Trust, London, UK.

PMID: 37866022
DOI: 10.1016/j.msard.2023.105045

Abstract

There is a lack of published guidelines on the management of patients with multiple sclerosis (MS) undergoing procedures that require anaesthesia and respective advice is largely based on retrospective studies or case reports. The aim of this paper is to provide recommendations for anaesthetists and neurologists for the management of patients with MS requiring anaesthesia. This review covers issues related to the anaesthetic management of patients with MS, with a focus on preoperative assessment, choice of anaesthetic techniques and agents, side-effects of drugs used during anaesthesia and their potential impact on the disease evolution, drug interactions that may occur, and the need to use monitoring devices. A systematic PubMed research was performed to retrieve relevant articles.

Keywords: Anaesthesia; Multiple sclerosis; Peri-operative management; Pregnancy; Preoperative assessment.

Publication types

Review

MeSH terms

Anesthetics*
Humans
Multiple Sclerosis* / therapy
Retrospective Studies

Substances

Anesthetics