"Selection of statistical tests influences the interpretation of a study outcome" a comment on "Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease. Prostaglandins Leukot Essent Fatty Acids. 2023 Jun; 193:102574. Doi: 10.1016/j.plefa.2023.102574. Epub 2023 Apr 7. PMID: 37121179"

Ashwin P Patel

doi:10.1016/j.plefa.2023.102591

"Selection of statistical tests influences the interpretation of a study outcome" a comment on "Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease. Prostaglandins Leukot Essent Fatty Acids. 2023 Jun; 193:102574. Doi: 10.1016/j.plefa.2023.102574. Epub 2023 Apr 7. PMID: 37121179"

Prostaglandins Leukot Essent Fatty Acids. 2023 Dec:198-199:102591. doi: 10.1016/j.plefa.2023.102591. Epub 2023 Oct 12.

Author

Ashwin P Patel¹

Affiliation

¹ Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, 2015 Upper Gate Drive, Atlanta, GA 30322, United States. Electronic address: apat261@emory.edu.

PMID: 37865611
DOI: 10.1016/j.plefa.2023.102591

Abstract

Parametric tests such as t-tests require a normal distribution of data. However, the determination of normal distribution may not be conclusive while dealing with a small sample size. Non-parametric tests such as Wilcoxon tests may be used in this situation, as these tests do not require normal distribution.

Keywords: Non-parametric test; Normal distribution; Parametric test.

Publication types

Letter

MeSH terms

Adult
Anemia, Sickle Cell* / drug therapy
Clinical Trials, Phase II as Topic
Docosahexaenoic Acids*
Humans
Multicenter Studies as Topic
Statistics as Topic

Substances

Docosahexaenoic Acids