Metasurfaces have shown extraordinary capability in individually manipulating various electromagnetic (EM) properties, including polarization, phase, and amplitude. However, it is still a challenge to manipulate these EM properties in one metasurface simultaneously. In this paper, a programmable multifunctional metasurface (PMFMS) is demonstrated with polarization, phase, and amplitude manipulation abilities. By controlling tunable coding states and changing the direction of incident waves, the PMFMS can operate as a transmission cross-polarization converter, spatial wave manipulator, and low-RCS radome. Besides, the PMFMS possesses an ultra-wideband property, which can operate from 6.5 to 10.2 GHz with 44.3% relative bandwidth. More importantly, multiple functionalities can also be achieved in reflection operating mode by reassembling the PMFMS. As a proof of concept, the PMFMS is fabricated and experimentally verified. Measured results are in good agreement with simulated results. Benefiting from multifunctional EM manipulations in an ultra-wideband, such a design can be applied in wireless communication systems, radar detection, and EM stealth platform.